The Hellforge quest within Act 4 will always drop some runes, and it is usually used as a payment for the speed of the act. The Countess's room D2R Ladder Items, at the bottom of the Forgotten Tower in Act 1's Black Marsh, is another excellent source for runes.Because Runes come with a specific level of rarity that ranges from commonly used (El) all the way to the rarest (Zod) They are often employed as an economy in Diablo 2.
El up to Lem are generally considered low runes, Pul and Gul are typically regarded as mid runes and Vex to Zod are usually considered high runes. If you see mid or high-level runes during your travels, be sure to keep them from being taken away at a moment's notice!
Runewords are some of the most impressive items that you can create to craft in Diablo 2: Resurrected, however, they require quite time to create. You'll need to first locate the appropriate runes that will create the runeword. Afterwards, you'll need to locate the weapon or armor, or shield that can accommodate the runeword.
The item has to have an exact number of sockets for the word to be effective and the runes need to be put into the item with sockets in the proper order. The item must also be plain (white); magic (blue) or rare (yellow) Buy D2R Ladder Items, unique (gold), as well as set (green) items with the appropriate amount of sockets won't work for runewords.